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M9550220.TXT
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1995-03-04
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Document 0220
DOCN M9550220
TI Evolution of immunological abnormalities in HIV infection by vertical
transmission.
DT 9505
AU Espanol T; Caragol I; Bertran JM; Immunology Unit, C.S. Valle Hebron,
Barcelona, Spain.
SO Acta Paediatr Suppl. 1994 Aug;400:35-8. Unique Identifier : AIDSLINE
MED/95135016
AB Forty-four children infected through vertical transmission, from a total
of 146 born to HIV-positive mothers, were studied. Immunological data
were analysed and compared with those of the noninfected children. Two
transmission patterns emerge from the clinical and immunological
characteristics: (i) infants infected during pregnancy with severe
immunodeficiency and clinical manifestations before the age of 1 year,
and (ii) children probably infected perinatally, who have better
clinical outcome. Immunological data are important for prognosis and
early therapeutic protocols to be established.
DE Case-Control Studies Child, Preschool Comparative Study CD4-Positive
T-Lymphocytes/IMMUNOLOGY Disease Transmission, Vertical Female Human
HIV Antibodies/BLOOD/IMMUNOLOGY HIV
Seropositivity/*IMMUNOLOGY/TRANSMISSION IgA/BLOOD/IMMUNOLOGY
IgG/BLOOD/IMMUNOLOGY IgM/BLOOD/IMMUNOLOGY Infant Interferon Type
II/BLOOD/IMMUNOLOGY Interleukin-1/BLOOD/IMMUNOLOGY
Interleukin-2/BLOOD/IMMUNOLOGY Mothers Prognosis Severity of Illness
Index JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).